Nicotine, the main ingredient in e-cigarettes, may affect users' mental state. While nicotine may cause a brief sense of relaxation when first ingested, it may cause users to feel more anxious and nervous as it depletes in the body. Long-term e-cigarette use may lead to nicotine dependence, further increasing the risk of anxiety.

Main ingredients in e-cigarettes
nicotine
Nicotine is one of the main ingredients in e-cigarettes and is often used to simulate the experience of traditional cigarettes. It is extracted from the tobacco plant and has stimulating and addictive properties. The concentration of nicotine varies in different e-cigarette liquids, from as low as 0mg/ml to as high as 50mg/ml or more. Although nicotine helps many people quit smoking, it also has some potential health risks, especially for minors and pregnant women.
liquid base
The liquid base is another main ingredient in e-cigarettes, usually consisting of vegetable glycerin (PG) and/or sucritol (VG). These ingredients provide a carrier for nicotine and flavors and determine the taste, smoke yield and power of the e-cigarette.
Vegetable glycerin (PG): This is a colorless, odorless liquid commonly used in food, medicine and cosmetics. PG produces better throat sensation and more "throat burn".
Sucritol (VG): More viscous than PG and can produce more steam. Because of its higher viscosity, it may cause clogging in some vaping devices.
The quality and price of liquid bases will vary depending on the brand and manufacturer, but generally speaking, 10ml of high-quality e-cigarette liquid will cost between $3-10.
Flavors and other additives
Flavors are an important ingredient in e-cigarettes, providing users with numerous flavor options, from traditional tobacco flavors to fruits, sweets, drinks and more. These flavors are often made from food-grade ingredients, but that doesn't mean they are safe to inhale.
In addition to flavors, some e-cigarette liquids may contain other additives such as colors, sweeteners or other chemicals to enhance the taste, color or stability of the product.
The definition and manifestation of anxiety
What is anxiety?
Anxiety is an emotional response that often involves worry or fear about future events. It can be a reaction to a specific situation, such as an exam, a job interview, or an upcoming big event, or it can be a general worry about something that is unclear or uncertain. Unlike brief periods of nervousness or worry, anxiety is a long-lasting feeling that may affect an individual's daily life. In some cases, anxiety can lead to more serious mental health problems if left untreated.
Common symptoms of anxiety
Symptoms of anxiety can range from mild to severe and involve physical, psychological and behavioral responses.
Physical symptoms: This includes rapid heartbeat, sweating, shaking or shaking, shortness of breath or feeling like you are choking, chest pain, nausea or diarrhea, and dizziness or lightheadedness.
Psychological symptoms: This includes persistent worry, fear, feelings of panic, excessive worry about daily tasks, being easily frightened or frightened, and feeling like things are getting out of control.
Behavioral symptoms: This includes avoiding certain places, activities, or people, needing to perform frequent ritualized behaviors (such as hand washing) to reduce anxiety, or avoiding certain things or decisions for an extended period of time.
The relationship between e-cigarettes and anxiety
Effects of Nicotine on Anxiety
Nicotine is a harsh chemical found in tobacco and e-cigarettes. Many people believe that nicotine relieves anxiety and stress, which is one of the reasons some people start smoking or vaping. However, while nicotine may provide a brief feeling of relaxation, it is not an effective way to reduce anxiety long-term.
When the body ingests nicotine, it stimulates the central nervous system, causing the release of "happy chemicals" such as dopamine. This feeling may be satisfying, but it is short-lived. As nicotine is consumed, the body may feel more anxious and tense, prompting the user to return to e-cigarettes or tobacco products. This leads to a cycle in which nicotine becomes a way to temporarily relieve the anxiety caused by no longer consuming nicotine, thus increasing nicotine dependence.
Research Evidence: Vaping and Anxiety Link
In recent years, there have been many studies trying to determine the relationship between e-cigarette use and anxiety. Some studies have found that e-cigarette users have higher anxiety levels than non-smokers. Although these studies provide valuable insights into the link between the two, more research is needed to determine the exact nature and causes of this link.
A study conducted in 2020 found that anxiety symptoms among e-cigarette users were related to nicotine intake, with users with high intakes reporting higher anxiety levels. This may be due to the physiological effects of nicotine, or due to other factors associated with e-cigarette use, such as health concerns or social pressure.
On the other hand, some users report that they turn to e-cigarettes because they are safer relative to traditional tobacco products, thus reducing their concerns about health consequences and thus reducing anxiety.
Other health risks
Effects of e-cigarettes on the lungs
E-cigarette use has been linked to a variety of lung problems. When users inhale e-cigarette vapor, they introduce nicotine, flavors and other chemicals directly into their lungs. These substances may cause or worsen breathing problems.
Inflammation: Certain ingredients in e-cigarette vapor may cause an inflammatory response in the lungs, which can increase the risk of asthma and other respiratory illnesses.
Chemical buildup: Although e-cigarette vapor is considered safer than traditional cigarette smoke, it still contains some chemicals that can be harmful to your lungs. For example, formaldehyde and vinyl alcohol have been shown to be present in some e-cigarette products.
EVALI: This is a lung disease associated with the use of e-cigarettes or heated tobacco products, primarily with THC products containing vitamin E acetate. Symptoms of EVALI include difficulty breathing, chest pain, and gastrointestinal symptoms.
E-cigarettes and other mental health issues
In addition to the anxieties mentioned above, e-cigarette use has been linked to a number of other mental health issues.
Dependence: Nicotine is a highly addictive substance. People who regularly use e-cigarettes may develop nicotine dependence, which can cause them to experience withdrawal symptoms such as anxiety, irritability, and depression when they try to quit.
Depression: Although the evidence is inconclusive, some studies suggest that e-cigarette use is associated with an increase in depressive symptoms. This may be due to nicotine's effects on neurotransmitters in the brain, or to social and environmental factors associated with e-cigarette use.
Behavioral problems: Especially among teenagers, e-cigarette use has been linked to behavioral problems, decreased school performance, and other mental health issues.

